T167-0821 Screening compound: N-[1-(1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidin-4-yl]-2,3-dimethoxybenzamide

T167-0821 Screening compound: N-[1-(1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidin-4-yl]-2,3-dimethoxybenzamide
T167-0821 Screening compound: N-[1-(1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidin-4-yl]-2,3-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T167-0821
N-[1-(1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidin-4-yl]-2,3-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T167-0821

Molecular Formula

C20H26N4O4 (C20 H26 N4 O4)

Compound Name

N-[1-(1-ethyl-6-oxo-1,6-dihydropyridazin-4-yl)piperidin-4-yl]-2,3-dimethoxybenzamide

IUPAC name

N-[1-(1-ethyl-6-oxo-16-dihydropyridazin-4-yl)piperidin-4-yl]-23-dimethoxybenzamide

SMILES

CCN1N=CC(N(CC2)CCC2NC(c(cccc2OC)c2OC)=O)=CC1=O

InChI

InChI=1S/C20H26N4O4/c1-4-24-18(25)12-15(13-21-24)23-10-8-14(9-11-23)22-20(26)16-6-5-7-17(27-2)19(16)28-3/h5-7,12-14H,4,8-11H2,1-3H3,(H,22,26)

InChI Key

MFMIZKFRMCXVEH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29002874

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.682

Distribution Coefficient, logD

1.672

Water Solubility, LogSw

-2.52

Polar Surface Area

71.784

Acid Dissociation Constant (pKa)

14.16

Base Dissociation Constant (pKb)

4.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

T167-0821 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Bromodomain Modulators Library (5801 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T167-0821 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T167-0821?
Check Price and Availability of T167-0821, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T167-0821 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T167-0821
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T167-0821
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T167-0821 available by request