T167-1430 Screening compound: N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2-(4-methylphenyl)acetamide

T167-1430 Screening compound: N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2-(4-methylphenyl)acetamide
T167-1430 Screening compound: N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2-(4-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T167-1430
N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2-(4-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T167-1430

Molecular Formula

C22H28N4O2 (C22 H28 N4 O2)

Compound Name

N-{1-[1-(cyclopropylmethyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperidin-4-yl}-2-(4-methylphenyl)acetamide

IUPAC name

N-{1-[1-(cyclopropylmethyl)-6-oxo-16-dihydropyridazin-4-yl]piperidin-4-yl}-2-(4-methylphenyl)acetamide

SMILES

Cc1ccc(CC(NC(CC2)CCN2C(C=NN2CC3CC3)=CC2=O)=O)cc1

InChI

InChI=1S/C22H28N4O2/c1-16-2-4-17(5-3-16)12-21(27)24-19-8-10-25(11-9-19)20-13-22(28)26(23-14-20)15-18-6-7-18/h2-5,13-14,18-19H,6-12,15H2,1H3,(H,24,27)

InChI Key

LIVKELQPUPVWCK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29002924

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.363

Distribution Coefficient, logD

2.352

Water Solubility, LogSw

-2.67

Polar Surface Area

56.750

Acid Dissociation Constant (pKa)

15.72

Base Dissociation Constant (pKb)

4.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

T167-1430 in Drug Discovery

Included in Screening Libraries

Bromodomain Modulators Library (5801 compounds)

CNS Targets (44014 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T167-1430 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T167-1430?
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What is the minimum amount of T167-1430 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T167-1430
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T167-1430
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T167-1430 available by request