T200-0130 Screening compound: 2-(3-methoxyphenyl)-5-(thiophene-3-carbonyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine

T200-0130 Screening compound: 2-(3-methoxyphenyl)-5-(thiophene-3-carbonyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine
T200-0130 Screening compound: 2-(3-methoxyphenyl)-5-(thiophene-3-carbonyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine alternative view

Chemical Structure Depiction of ChemDiv screening compound T200-0130
2-(3-methoxyphenyl)-5-(thiophene-3-carbonyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T200-0130

Molecular Formula

C19H19N3O2S (C19 H19 N3 O2 S)

Compound Name

2-(3-methoxyphenyl)-5-(thiophene-3-carbonyl)-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,4]diazepine

IUPAC name

2-(3-methoxyphenyl)-5-(thiophene-3-carbonyl)-4H5H6H7H8H-pyrazolo[15-a][14]diazepine

SMILES

COc1cccc(-c2nn(CCCN(C3)C(c4cscc4)=O)c3c2)c1

InChI

InChI=1S/C19H19N3O2S/c1-24-17-5-2-4-14(10-17)18-11-16-12-21(7-3-8-22(16)20-18)19(23)15-6-9-25-13-15/h2,4-6,9-11,13H,3,7-8,12H2,1H3

InChI Key

XOZPTLALEUVRBF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27618594

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.000

Distribution Coefficient, logD

3.000

Water Solubility, LogSw

-3.22

Polar Surface Area

38.979

Acid Dissociation Constant (pKa)

27.18

Base Dissociation Constant (pKb)

-0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

T200-0130 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with T200-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T200-0130?
Check Price and Availability of T200-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T200-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T200-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T200-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T200-0130 available by request