T226-1018 Screening compound: 7-(4-cyclohexylpiperazine-1-carbonyl)-5-methyl-4H,5H-pyrazolo[1,5-a]quinoxalin-4-one

T226-1018 Screening compound: 7-(4-cyclohexylpiperazine-1-carbonyl)-5-methyl-4H,5H-pyrazolo[1,5-a]quinoxalin-4-one
T226-1018 Screening compound: 7-(4-cyclohexylpiperazine-1-carbonyl)-5-methyl-4H,5H-pyrazolo[1,5-a]quinoxalin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T226-1018
7-(4-cyclohexylpiperazine-1-carbonyl)-5-methyl-4H,5H-pyrazolo[1,5-a]quinoxalin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T226-1018

Molecular Formula

C22H27N5O2 (C22 H27 N5 O2)

Compound Name

7-(4-cyclohexylpiperazine-1-carbonyl)-5-methyl-4H,5H-pyrazolo[1,5-a]quinoxalin-4-one

IUPAC name

7-(4-cyclohexylpiperazine-1-carbonyl)-5-methyl-4H5H-pyrazolo[15-a]quinoxalin-4-one

SMILES

CN(c(cc(cc1)C(N(CC2)CCN2C2CCCCC2)=O)c1-n1nccc11)C1=O

InChI

InChI=1S/C22H27N5O2/c1-24-20-15-16(7-8-18(20)27-19(22(24)29)9-10-23-27)21(28)26-13-11-25(12-14-26)17-5-3-2-4-6-17/h7-10,15,17H,2-6,11-14H2,1H3

InChI Key

NZPXOFZZORUZEN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29023044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.707

Distribution Coefficient, logD

1.544

Water Solubility, LogSw

-2.04

Polar Surface Area

47.618

Acid Dissociation Constant (pKa)

28.39

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

T226-1018 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

CNS BBB Library (22607 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T226-1018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T226-1018?
Check Price and Availability of T226-1018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T226-1018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T226-1018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T226-1018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T226-1018 available by request