T226-1280 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-5-ethyl-4-oxo-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide

T226-1280 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-5-ethyl-4-oxo-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide
T226-1280 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-5-ethyl-4-oxo-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T226-1280
N-[(2-chloro-4-fluorophenyl)methyl]-5-ethyl-4-oxo-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T226-1280

Molecular Formula

C20H16ClFN4O2 (C20 H16 ClFN4 O2)

Compound Name

N-[(2-chloro-4-fluorophenyl)methyl]-5-ethyl-4-oxo-4H,5H-pyrazolo[1,5-a]quinoxaline-7-carboxamide

IUPAC name

N-[(2-chloro-4-fluorophenyl)methyl]-5-ethyl-4-oxo-4H5H-pyrazolo[15-a]quinoxaline-7-carboxamide

SMILES

CCN(c(cc(cc1)C(NCc(ccc(F)c2)c2Cl)=O)c1-n1nccc11)C1=O

InChI

InChI=1S/C20H16ClFN4O2/c1-2-25-18-9-12(4-6-16(18)26-17(20(25)28)7-8-24-26)19(27)23-11-13-3-5-14(22)10-15(13)21/h3-10H,2,11H2,1H3,(H,23,27)

InChI Key

IZCMXDBRINQEFS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29023142

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.82

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.278

Distribution Coefficient, logD

3.278

Water Solubility, LogSw

-3.68

Polar Surface Area

52.249

Acid Dissociation Constant (pKa)

11.75

Base Dissociation Constant (pKb)

-0.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

T226-1280 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T226-1280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T226-1280?
Check Price and Availability of T226-1280, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T226-1280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T226-1280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T226-1280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T226-1280 available by request