T368-0049 Screening compound: CYCLOBUTYL[3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINYL]METHANONE

T368-0049 Screening compound: CYCLOBUTYL[3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINYL]METHANONE
T368-0049 Screening compound: CYCLOBUTYL[3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINYL]METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-0049
CYCLOBUTYL[3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINYL]METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-0049

Molecular Formula

C18H24N4O (C18 H24 N4 O)

Compound Name

CYCLOBUTYL[3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINYL]METHANONE

IUPAC name

n/a

SMILES

CCCc1nc2cccnc2n1C(CC1)CN1C(C1CCC1)=O

InChI

InChI=1S/C18H24N4O/c1-2-5-16-20-15-8-4-10-19-17(15)22(16)14-9-11-21(12-14)18(23)13-6-3-7-13/h4,8,10,13-14H,2-3,5-7,9,11-12H2,1H3/t14-/m1/s1

InChI Key

HHPFRCYLQTVOBU-CQSZACIVSA-N

MDL Number (MFCD)

MFCD29032453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

312.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.185

Distribution Coefficient, logD

2.185

Water Solubility, LogSw

-2.14

Polar Surface Area

38.905

Acid Dissociation Constant (pKa)

19.00

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.10

T368-0049 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T368-0049 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-0049?
Check Price and Availability of T368-0049, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-0049 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-0049
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-0049
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-0049 available by request