T368-0255 Screening compound: 3-(3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carbonyl)-1-ethyl-1H-pyrazole

T368-0255 Screening compound: 3-(3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carbonyl)-1-ethyl-1H-pyrazole
T368-0255 Screening compound: 3-(3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carbonyl)-1-ethyl-1H-pyrazole alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-0255
3-(3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carbonyl)-1-ethyl-1H-pyrazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-0255

Molecular Formula

C21H26N6O (C21 H26 N6 O)

Compound Name

3-(3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carbonyl)-1-ethyl-1H-pyrazole

IUPAC name

3-(3-{2-cyclopentyl-3H-imidazo[45-b]pyridin-3-yl}pyrrolidine-1-carbonyl)-1-ethyl-1H-pyrazole

SMILES

CCn(cc1)nc1C(N(CC1)CC1n1c2ncccc2nc1C1CCCC1)=O

InChI

InChI=1S/C21H26N6O/c1-2-26-13-10-18(24-26)21(28)25-12-9-16(14-25)27-19(15-6-3-4-7-15)23-17-8-5-11-22-20(17)27/h5,8,10-11,13,15-16H,2-4,6-7,9,12,14H2,1H3/t16-/m1/s1

InChI Key

VCSYOBYBAHWQLK-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD29023249

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.381

Distribution Coefficient, logD

2.381

Water Solubility, LogSw

-2.36

Polar Surface Area

52.077

Acid Dissociation Constant (pKa)

19.51

Base Dissociation Constant (pKb)

3.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

52.40

T368-0255 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-0255 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-0255?
Check Price and Availability of T368-0255, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-0255 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-0255
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-0255
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-0255 available by request