T368-0653 Screening compound: 2-ETHOXY-1-{3-[2-(4-METHOXYPHENYL)-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL]PYRROLIDIN-1-YL}ETHAN-1-ONE

T368-0653 Screening compound: 2-ETHOXY-1-{3-[2-(4-METHOXYPHENYL)-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL]PYRROLIDIN-1-YL}ETHAN-1-ONE
T368-0653 Screening compound: 2-ETHOXY-1-{3-[2-(4-METHOXYPHENYL)-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL]PYRROLIDIN-1-YL}ETHAN-1-ONE alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-0653
2-ETHOXY-1-{3-[2-(4-METHOXYPHENYL)-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL]PYRROLIDIN-1-YL}ETHAN-1-ONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-0653

Molecular Formula

C21H24N4O3 (C21 H24 N4 O3)

Compound Name

2-ETHOXY-1-{3-[2-(4-METHOXYPHENYL)-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL]PYRROLIDIN-1-YL}ETHAN-1-ONE

IUPAC name

n/a

SMILES

CCOCC(N(CC1)CC1n1c(-c(cc2)ccc2OC)nc2cccnc12)=O

InChI

InChI=1S/C21H24N4O3/c1-3-28-14-19(26)24-12-10-16(13-24)25-20(15-6-8-17(27-2)9-7-15)23-18-5-4-11-22-21(18)25/h4-9,11,16H,3,10,12-14H2,1-2H3/t16-/m1/s1

InChI Key

JIWVHFYNRWWPLI-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD27618821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.224

Distribution Coefficient, logD

2.224

Water Solubility, LogSw

-2.21

Polar Surface Area

52.481

Acid Dissociation Constant (pKa)

17.43

Base Dissociation Constant (pKb)

2.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

T368-0653 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-0653 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-0653?
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What is the minimum amount of T368-0653 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-0653
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-0653
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-0653 available by request