T368-0838 Screening compound: 1-ethyl-5-{3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}-1H-pyrazole

T368-0838 Screening compound: 1-ethyl-5-{3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}-1H-pyrazole
T368-0838 Screening compound: 1-ethyl-5-{3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}-1H-pyrazole alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-0838
1-ethyl-5-{3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}-1H-pyrazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-0838

Molecular Formula

C22H21FN6O (C22 H21 FN6 O)

Compound Name

1-ethyl-5-{3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carbonyl}-1H-pyrazole

IUPAC name

n/a

SMILES

CCn1nccc1C(N(CC1)CC1n1c(-c(cc2)ccc2F)nc2c1nccc2)=O

InChI

InChI=1S/C22H21FN6O/c1-2-28-19(9-12-25-28)22(30)27-13-10-17(14-27)29-20(15-5-7-16(23)8-6-15)26-18-4-3-11-24-21(18)29/h3-9,11-12,17H,2,10,13-14H2,1H3/t17-/m0/s1

InChI Key

ITYBITIDZBNAAD-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD29023266

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.624

Distribution Coefficient, logD

2.624

Water Solubility, LogSw

-2.53

Polar Surface Area

50.223

Acid Dissociation Constant (pKa)

17.35

Base Dissociation Constant (pKb)

2.61

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

T368-0838 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-0838 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-0838?
Check Price and Availability of T368-0838, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-0838 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-0838
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-0838
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-0838 available by request