T368-1429 Screening compound: 1-{3-[2-(furan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidin-1-yl}-2-(thiophen-2-yl)ethan-1-one

T368-1429 Screening compound: 1-{3-[2-(furan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidin-1-yl}-2-(thiophen-2-yl)ethan-1-one
T368-1429 Screening compound: 1-{3-[2-(furan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidin-1-yl}-2-(thiophen-2-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-1429
1-{3-[2-(furan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidin-1-yl}-2-(thiophen-2-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-1429

Molecular Formula

C20H18N4O2S (C20 H18 N4 O2 S)

Compound Name

1-{3-[2-(furan-2-yl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidin-1-yl}-2-(thiophen-2-yl)ethan-1-one

IUPAC name

1-{3-[2-(furan-2-yl)-3H-imidazo[45-b]pyridin-3-yl]pyrrolidin-1-yl}-2-(thiophen-2-yl)ethan-1-one

SMILES

O=C(Cc1cccs1)N(CC1)CC1n1c2ncccc2nc1-c1ccco1

InChI

InChI=1S/C20H18N4O2S/c25-18(12-15-4-3-11-27-15)23-9-7-14(13-23)24-19-16(5-1-8-21-19)22-20(24)17-6-2-10-26-17/h1-6,8,10-11,14H,7,9,12-13H2/t14-/m1/s1

InChI Key

UZNRPJGPUIEXQM-CQSZACIVSA-N

MDL Number (MFCD)

MFCD29023285

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.467

Distribution Coefficient, logD

2.467

Water Solubility, LogSw

-2.39

Polar Surface Area

46.203

Acid Dissociation Constant (pKa)

18.26

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

T368-1429 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-1429 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-1429?
Check Price and Availability of T368-1429, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-1429 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-1429
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-1429
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-1429 available by request