T368-1762 Screening compound: N-(3-METHOXYBENZYL)-3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINECARBOXAMIDE

T368-1762 Screening compound: N-(3-METHOXYBENZYL)-3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINECARBOXAMIDE
T368-1762 Screening compound: N-(3-METHOXYBENZYL)-3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-1762
N-(3-METHOXYBENZYL)-3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-1762

Molecular Formula

C22H27N5O2 (C22 H27 N5 O2)

Compound Name

N-(3-METHOXYBENZYL)-3-(2-PROPYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)-1-PYRROLIDINECARBOXAMIDE

IUPAC name

N-[(3-methoxyphenyl)methyl]-3-{2-propyl-3H-imidazo[45-b]pyridin-3-yl}pyrrolidine-1-carboxamide

SMILES

CCCc1nc2cccnc2n1C(CC1)CN1C(NCc1cc(OC)ccc1)=O

InChI

InChI=1S/C22H27N5O2/c1-3-6-20-25-19-9-5-11-23-21(19)27(20)17-10-12-26(15-17)22(28)24-14-16-7-4-8-18(13-16)29-2/h4-5,7-9,11,13,17H,3,6,10,12,14-15H2,1-2H3,(H,24,28)/t17-/m1/s1

InChI Key

IHVWVOUXLXSQBM-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD29023297

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.012

Distribution Coefficient, logD

3.012

Water Solubility, LogSw

-3.17

Polar Surface Area

56.069

Acid Dissociation Constant (pKa)

14.64

Base Dissociation Constant (pKb)

2.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.91

T368-1762 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-1762 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-1762?
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What is the minimum amount of T368-1762 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-1762
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-1762
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-1762 available by request