T368-1867 Screening compound: N-benzyl-3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carboxamide

T368-1867 Screening compound: N-benzyl-3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carboxamide
T368-1867 Screening compound: N-benzyl-3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-1867
N-benzyl-3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-1867

Molecular Formula

C23H27N5O (C23 H27 N5 O)

Compound Name

N-benzyl-3-{2-cyclopentyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidine-1-carboxamide

IUPAC name

N-benzyl-3-{2-cyclopentyl-3H-imidazo[45-b]pyridin-3-yl}pyrrolidine-1-carboxamide

SMILES

O=C(NCc1ccccc1)N(CC1)CC1n1c2ncccc2nc1C1CCCC1

InChI

InChI=1S/C23H27N5O/c29-23(25-15-17-7-2-1-3-8-17)27-14-12-19(16-27)28-21(18-9-4-5-10-18)26-20-11-6-13-24-22(20)28/h1-3,6-8,11,13,18-19H,4-5,9-10,12,14-16H2,(H,25,29)/t19-/m1/s1

InChI Key

FVXNOSXUQMBTQN-LJQANCHMSA-N

MDL Number (MFCD)

MFCD29023307

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.472

Distribution Coefficient, logD

3.472

Water Solubility, LogSw

-3.43

Polar Surface Area

47.835

Acid Dissociation Constant (pKa)

14.14

Base Dissociation Constant (pKb)

3.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

T368-1867 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

KRAS-Targeted Library (16000 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-1867 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-1867?
Check Price and Availability of T368-1867, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-1867 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-1867
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-1867
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-1867 available by request