T368-2381 Screening compound: N-tert-butyl-3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide

T368-2381 Screening compound: N-tert-butyl-3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide
T368-2381 Screening compound: N-tert-butyl-3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-2381
N-tert-butyl-3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-2381

Molecular Formula

C21H24FN5O (C21 H24 FN5 O)

Compound Name

N-tert-butyl-3-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]pyrrolidine-1-carboxamide

IUPAC name

N-tert-butyl-3-[2-(4-fluorophenyl)-3H-imidazo[45-b]pyridin-3-yl]pyrrolidine-1-carboxamide

SMILES

CC(C)(C)NC(N(CC1)CC1n1c(-c(cc2)ccc2F)nc2c1nccc2)=O

InChI

InChI=1S/C21H24FN5O/c1-21(2,3)25-20(28)26-12-10-16(13-26)27-18(14-6-8-15(22)9-7-14)24-17-5-4-11-23-19(17)27/h4-9,11,16H,10,12-13H2,1-3H3,(H,25,28)/t16-/m0/s1

InChI Key

NRUWKWBPCMFACW-INIZCTEOSA-N

MDL Number (MFCD)

MFCD29023325

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.749

Distribution Coefficient, logD

3.749

Water Solubility, LogSw

-3.88

Polar Surface Area

46.372

Acid Dissociation Constant (pKa)

16.20

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

T368-2381 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-2381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-2381?
Check Price and Availability of T368-2381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-2381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-2381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-2381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-2381 available by request