T368-3081 Screening compound: N-{4-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]phenyl}acetamide

T368-3081 Screening compound: N-{4-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]phenyl}acetamide
T368-3081 Screening compound: N-{4-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]phenyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-3081
N-{4-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]phenyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-3081

Molecular Formula

C21H25N5O3S (C21 H25 N5 O3 S)

Compound Name

N-{4-[(3-{2-propyl-3H-imidazo[4,5-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]phenyl}acetamide

IUPAC name

N-{4-[(3-{2-propyl-3H-imidazo[45-b]pyridin-3-yl}pyrrolidin-1-yl)sulfonyl]phenyl}acetamide

SMILES

CCCc1nc2cccnc2n1C(CC1)CN1S(c(cc1)ccc1NC(C)=O)(=O)=O

InChI

InChI=1S/C21H25N5O3S/c1-3-5-20-24-19-6-4-12-22-21(19)26(20)17-11-13-25(14-17)30(28,29)18-9-7-16(8-10-18)23-15(2)27/h4,6-10,12,17H,3,5,11,13-14H2,1-2H3,(H,23,27)/t17-/m1/s1

InChI Key

OXXLBVKEAMCEGT-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD29023869

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.332

Distribution Coefficient, logD

2.332

Water Solubility, LogSw

-2.69

Polar Surface Area

76.706

Acid Dissociation Constant (pKa)

10.53

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

T368-3081 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-3081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-3081?
Check Price and Availability of T368-3081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T368-3081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-3081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-3081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-3081 available by request