T368-3397 Screening compound: 3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-(propane-1-sulfonyl)pyrrolidine

T368-3397 Screening compound: 3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-(propane-1-sulfonyl)pyrrolidine
T368-3397 Screening compound: 3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-(propane-1-sulfonyl)pyrrolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound T368-3397
3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-(propane-1-sulfonyl)pyrrolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T368-3397

Molecular Formula

C20H24N4O2S (C20 H24 N4 O2 S)

Compound Name

3-[2-(4-methylphenyl)-3H-imidazo[4,5-b]pyridin-3-yl]-1-(propane-1-sulfonyl)pyrrolidine

IUPAC name

3-[2-(4-methylphenyl)-3H-imidazo[45-b]pyridin-3-yl]-1-(propane-1-sulfonyl)pyrrolidine

SMILES

CCCS(N(CC1)CC1n1c(-c2ccc(C)cc2)nc2cccnc12)(=O)=O

InChI

InChI=1S/C20H24N4O2S/c1-3-13-27(25,26)23-12-10-17(14-23)24-19(16-8-6-15(2)7-9-16)22-18-5-4-11-21-20(18)24/h4-9,11,17H,3,10,12-14H2,1-2H3/t17-/m1/s1

InChI Key

NQTVYHASSXTFJQ-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD29023350

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.320

Distribution Coefficient, logD

3.320

Water Solubility, LogSw

-3.37

Polar Surface Area

52.363

Acid Dissociation Constant (pKa)

17.36

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

T368-3397 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T368-3397 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T368-3397?
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What is the minimum amount of T368-3397 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T368-3397
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T368-3397
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T368-3397 available by request