T387-0415 Screening compound: {1-[5-(3-fluorophenyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidyl}(morpholino)methanone

T387-0415 Screening compound: {1-[5-(3-fluorophenyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidyl}(morpholino)methanone
T387-0415 Screening compound: {1-[5-(3-fluorophenyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidyl}(morpholino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-0415
{1-[5-(3-fluorophenyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidyl}(morpholino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-0415

Molecular Formula

C22H23FN4O2S (C22 H23 FN4 O2 S)

Compound Name

{1-[5-(3-fluorophenyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidyl}(morpholino)methanone

IUPAC name

4-{1-[5-(3-fluorophenyl)-[13]thiazolo[54-b]pyridin-2-yl]piperidine-4-carbonyl}morpholine

SMILES

O=C(C(CC1)CCN1c1nc2ccc(-c3cc(F)ccc3)nc2s1)N1CCOCC1

InChI

InChI=1S/C22H23FN4O2S/c23-17-3-1-2-16(14-17)18-4-5-19-20(24-18)30-22(25-19)27-8-6-15(7-9-27)21(28)26-10-12-29-13-11-26/h1-5,14-15H,6-13H2

InChI Key

HMPWNJVOXODDPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619060

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.950

Distribution Coefficient, logD

3.922

Water Solubility, LogSw

-4.05

Polar Surface Area

46.485

Acid Dissociation Constant (pKa)

20.97

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.91

T387-0415 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T387-0415 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-0415?
Check Price and Availability of T387-0415, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-0415 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-0415
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-0415
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-0415 available by request