T387-0878 Screening compound: N-(3-methylbutyl)-1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

T387-0878 Screening compound: N-(3-methylbutyl)-1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide
T387-0878 Screening compound: N-(3-methylbutyl)-1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-0878
N-(3-methylbutyl)-1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-0878

Molecular Formula

C21H26N6OS (C21 H26 N6 OS)

Compound Name

N-(3-methylbutyl)-1-[5-(pyrimidin-5-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

IUPAC name

N-(3-methylbutyl)-1-[5-(pyrimidin-5-yl)-[13]thiazolo[54-b]pyridin-2-yl]piperidine-4-carboxamide

SMILES

CC(C)CCNC(C(CC1)CCN1c1nc2ccc(-c3cncnc3)nc2s1)=O

InChI

InChI=1S/C21H26N6OS/c1-14(2)5-8-24-19(28)15-6-9-27(10-7-15)21-26-18-4-3-17(25-20(18)29-21)16-11-22-13-23-12-16/h3-4,11-15H,5-10H2,1-2H3,(H,24,28)

InChI Key

UAQIPNANKBRTPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619130

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.051

Distribution Coefficient, logD

2.613

Water Solubility, LogSw

-3.01

Polar Surface Area

67.205

Acid Dissociation Constant (pKa)

13.75

Base Dissociation Constant (pKb)

7.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

T387-0878 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T387-0878 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-0878?
Check Price and Availability of T387-0878, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-0878 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-0878
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-0878
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-0878 available by request