T387-0914 Screening compound: N-(2-methoxyethyl)-1-[5-(5-pyrimidinyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidinecarboxamide

T387-0914 Screening compound: N-(2-methoxyethyl)-1-[5-(5-pyrimidinyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidinecarboxamide
T387-0914 Screening compound: N-(2-methoxyethyl)-1-[5-(5-pyrimidinyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-0914
N-(2-methoxyethyl)-1-[5-(5-pyrimidinyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-0914

Molecular Formula

C19H22N6O2S (C19 H22 N6 O2 S)

Compound Name

N-(2-methoxyethyl)-1-[5-(5-pyrimidinyl)[1,3]thiazolo[5,4-b]pyridin-2-yl]-4-piperidinecarboxamide

IUPAC name

N-(2-methoxyethyl)-1-[5-(pyrimidin-5-yl)-[13]thiazolo[54-b]pyridin-2-yl]piperidine-4-carboxamide

SMILES

COCCNC(C(CC1)CCN1c1nc2ccc(-c3cncnc3)nc2s1)=O

InChI

InChI=1S/C19H22N6O2S/c1-27-9-6-22-17(26)13-4-7-25(8-5-13)19-24-16-3-2-15(23-18(16)28-19)14-10-20-12-21-11-14/h2-3,10-13H,4-9H2,1H3,(H,22,26)

InChI Key

VEZGCAHEKJJDJH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619147

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.518

Distribution Coefficient, logD

1.079

Water Solubility, LogSw

-1.90

Polar Surface Area

75.547

Acid Dissociation Constant (pKa)

14.01

Base Dissociation Constant (pKb)

7.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

T387-0914 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with T387-0914 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-0914?
Check Price and Availability of T387-0914, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-0914 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-0914
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-0914
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-0914 available by request