T387-1027 Screening compound: 3-{2-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]-[1,3]thiazolo[5,4-b]pyridin-5-yl}pyridine

T387-1027 Screening compound: 3-{2-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]-[1,3]thiazolo[5,4-b]pyridin-5-yl}pyridine
T387-1027 Screening compound: 3-{2-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]-[1,3]thiazolo[5,4-b]pyridin-5-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-1027
3-{2-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]-[1,3]thiazolo[5,4-b]pyridin-5-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-1027

Molecular Formula

C21H23N5OS (C21 H23 N5 OS)

Compound Name

3-{2-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]-[1,3]thiazolo[5,4-b]pyridin-5-yl}pyridine

IUPAC name

3-{2-[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]-[13]thiazolo[54-b]pyridin-5-yl}pyridine

SMILES

O=C(C(CC1)CCN1c1nc2ccc(-c3cnccc3)nc2s1)N1CCCC1

InChI

InChI=1S/C21H23N5OS/c27-20(25-10-1-2-11-25)15-7-12-26(13-8-15)21-24-18-6-5-17(23-19(18)28-21)16-4-3-9-22-14-16/h3-6,9,14-15H,1-2,7-8,10-13H2

InChI Key

DNNXLJILHPVTLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619179

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.415

Distribution Coefficient, logD

3.387

Water Solubility, LogSw

-3.25

Polar Surface Area

48.460

Acid Dissociation Constant (pKa)

20.97

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

T387-1027 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T387-1027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-1027?
Check Price and Availability of T387-1027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-1027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-1027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-1027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-1027 available by request