T387-1208 Screening compound: N,N-diethyl-1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

T387-1208 Screening compound: N,N-diethyl-1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide
T387-1208 Screening compound: N,N-diethyl-1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-1208
N,N-diethyl-1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-1208

Molecular Formula

C20H24N4OS2 (C20 H24 N4 OS2)

Compound Name

N,N-diethyl-1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

IUPAC name

NN-diethyl-1-[5-(thiophen-2-yl)-[13]thiazolo[54-b]pyridin-2-yl]piperidine-4-carboxamide

SMILES

CCN(CC)C(C(CC1)CCN1c1nc2ccc(-c3cccs3)nc2s1)=O

InChI

InChI=1S/C20H24N4OS2/c1-3-23(4-2)19(25)14-9-11-24(12-10-14)20-22-16-8-7-15(21-18(16)27-20)17-6-5-13-26-17/h5-8,13-14H,3-4,9-12H2,1-2H3

InChI Key

ACZZCYUSLQXYRO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619224

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.57

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.601

Distribution Coefficient, logD

4.573

Water Solubility, LogSw

-4.28

Polar Surface Area

38.879

Acid Dissociation Constant (pKa)

20.97

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

T387-1208 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T387-1208 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-1208?
Check Price and Availability of T387-1208, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-1208 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-1208
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-1208
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-1208 available by request