T387-1239 Screening compound: 1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

T387-1239 Screening compound: 1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide
T387-1239 Screening compound: 1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T387-1239
1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T387-1239

Molecular Formula

C16H16N4OS2 (C16 H16 N4 OS2)

Compound Name

1-[5-(thiophen-2-yl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]piperidine-4-carboxamide

IUPAC name

1-[5-(thiophen-2-yl)-[13]thiazolo[54-b]pyridin-2-yl]piperidine-4-carboxamide

SMILES

NC(C(CC1)CCN1c1nc2ccc(-c3cccs3)nc2s1)=O

InChI

InChI=1S/C16H16N4OS2/c17-14(21)10-5-7-20(8-6-10)16-19-12-4-3-11(18-15(12)23-16)13-2-1-9-22-13/h1-4,9-10H,5-8H2,(H2,17,21)

InChI Key

DGBXPQFNTXHRHH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619234

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.223

Distribution Coefficient, logD

3.204

Water Solubility, LogSw

-3.13

Polar Surface Area

57.006

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

6.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.25

T387-1239 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with T387-1239 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T387-1239?
Check Price and Availability of T387-1239, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T387-1239 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T387-1239
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T387-1239
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T387-1239 available by request