T403-1323 Screening compound: N-(5-chloro-2-fluorophenyl)-1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidine-4-carboxamide

T403-1323 Screening compound: N-(5-chloro-2-fluorophenyl)-1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidine-4-carboxamide
T403-1323 Screening compound: N-(5-chloro-2-fluorophenyl)-1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T403-1323
N-(5-chloro-2-fluorophenyl)-1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T403-1323

Molecular Formula

C18H17ClFN5O (C18 H17 ClFN5 O)

Compound Name

N-(5-chloro-2-fluorophenyl)-1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidine-4-carboxamide

IUPAC name

N-(5-chloro-2-fluorophenyl)-1-{[124]triazolo[43-a]pyridin-3-yl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1nnc2n1cccc2)Nc(cc(cc1)Cl)c1F

InChI

InChI=1S/C18H17ClFN5O/c19-13-4-5-14(20)15(11-13)21-17(26)12-6-9-24(10-7-12)18-23-22-16-3-1-2-8-25(16)18/h1-5,8,11-12H,6-7,9-10H2,(H,21,26)

InChI Key

KABHLRMHBIGCCX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619394

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.82

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.951

Distribution Coefficient, logD

2.900

Water Solubility, LogSw

-3.54

Polar Surface Area

47.235

Acid Dissociation Constant (pKa)

8.31

Base Dissociation Constant (pKb)

10.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.78

T403-1323 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with T403-1323 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T403-1323?
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What is the minimum amount of T403-1323 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T403-1323
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T403-1323
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T403-1323 available by request