T403-2398 Screening compound: N-(2-piperidinoethyl)-1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-3-piperidinecarboxamide

T403-2398 Screening compound: N-(2-piperidinoethyl)-1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-3-piperidinecarboxamide
T403-2398 Screening compound: N-(2-piperidinoethyl)-1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T403-2398
N-(2-piperidinoethyl)-1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T403-2398

Molecular Formula

C19H28N6O (C19 H28 N6 O)

Compound Name

N-(2-piperidinoethyl)-1-[1,2,4]triazolo[4,3-a]pyridin-3-yl-3-piperidinecarboxamide

IUPAC name

N-[2-(piperidin-1-yl)ethyl]-1-{[124]triazolo[43-a]pyridin-3-yl}piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1nnc2n1cccc2)NCCN1CCCCC1

InChI

InChI=1S/C19H28N6O/c26-18(20-9-14-23-10-3-1-4-11-23)16-7-6-12-24(15-16)19-22-21-17-8-2-5-13-25(17)19/h2,5,8,13,16H,1,3-4,6-7,9-12,14-15H2,(H,20,26)/t16-/m0/s1

InChI Key

IUQWKTPDEVHYAC-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27619524

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.011

Distribution Coefficient, logD

-0.796

Water Solubility, LogSw

-1.59

Polar Surface Area

53.013

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

9.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

63.16

T403-2398 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T403-2398 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T403-2398?
Check Price and Availability of T403-2398, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T403-2398 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T403-2398
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T403-2398
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T403-2398 available by request