T403-2549 Screening compound: [1-(8-chloro[1,2,4]triazolo[4,3-a]pyridin-3-yl)-3-piperidyl](4-ethylpiperazino)methanone

T403-2549 Screening compound: [1-(8-chloro[1,2,4]triazolo[4,3-a]pyridin-3-yl)-3-piperidyl](4-ethylpiperazino)methanone
T403-2549 Screening compound: [1-(8-chloro[1,2,4]triazolo[4,3-a]pyridin-3-yl)-3-piperidyl](4-ethylpiperazino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T403-2549
[1-(8-chloro[1,2,4]triazolo[4,3-a]pyridin-3-yl)-3-piperidyl](4-ethylpiperazino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T403-2549

Molecular Formula

C18H25ClN6O (C18 H25 ClN6 O)

Compound Name

[1-(8-chloro[1,2,4]triazolo[4,3-a]pyridin-3-yl)-3-piperidyl](4-ethylpiperazino)methanone

IUPAC name

1-(1-{8-chloro-[124]triazolo[43-a]pyridin-3-yl}piperidine-3-carbonyl)-4-ethylpiperazine

SMILES

CCN(CC1)CCN1C(C(CCC1)CN1c1nnc2n1cccc2Cl)=O

InChI

InChI=1S/C18H25ClN6O/c1-2-22-9-11-23(12-10-22)17(26)14-5-3-7-24(13-14)18-21-20-16-15(19)6-4-8-25(16)18/h4,6,8,14H,2-3,5,7,9-13H2,1H3/t14-/m0/s1

InChI Key

LFFQEZPOFHEMLJ-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27619587

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.237

Distribution Coefficient, logD

0.797

Water Solubility, LogSw

-2.38

Polar Surface Area

45.507

Acid Dissociation Constant (pKa)

21.56

Base Dissociation Constant (pKb)

7.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.11

T403-2549 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T403-2549 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T403-2549?
Check Price and Availability of T403-2549, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T403-2549 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T403-2549
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T403-2549
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T403-2549 available by request