T403-2819 Screening compound: 4-{1-[6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidine-3-carbonyl}morpholine

T403-2819 Screening compound: 4-{1-[6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidine-3-carbonyl}morpholine
T403-2819 Screening compound: 4-{1-[6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidine-3-carbonyl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound T403-2819
4-{1-[6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidine-3-carbonyl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T403-2819

Molecular Formula

C17H20F3N5O2 (C17 H20 F3 N5 O2)

Compound Name

4-{1-[6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]piperidine-3-carbonyl}morpholine

IUPAC name

4-{1-[6-(trifluoromethyl)-[124]triazolo[43-a]pyridin-3-yl]piperidine-3-carbonyl}morpholine

SMILES

O=C(C(CCC1)CN1c1nnc2n1cc(C(F)(F)F)cc2)N1CCOCC1

InChI

InChI=1S/C17H20F3N5O2/c18-17(19,20)13-3-4-14-21-22-16(25(14)11-13)24-5-1-2-12(10-24)15(26)23-6-8-27-9-7-23/h3-4,11-12H,1-2,5-10H2/t12-/m0/s1

InChI Key

CGJPNQSEVTXMOX-LBPRGKRZSA-N

MDL Number (MFCD)

MFCD27619705

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.359

Distribution Coefficient, logD

1.359

Water Solubility, LogSw

-1.64

Polar Surface Area

49.225

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

8.04

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

58.82

T403-2819 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with T403-2819 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T403-2819?
Check Price and Availability of T403-2819, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T403-2819 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T403-2819
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T403-2819
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T403-2819 available by request