T404-1539 Screening compound: 5-chloro-N-(1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidin-4-yl)thiophene-2-carboxamide

T404-1539 Screening compound: 5-chloro-N-(1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidin-4-yl)thiophene-2-carboxamide
T404-1539 Screening compound: 5-chloro-N-(1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidin-4-yl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T404-1539
5-chloro-N-(1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidin-4-yl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T404-1539

Molecular Formula

C16H16ClN5OS (C16 H16 ClN5 OS)

Compound Name

5-chloro-N-(1-{[1,2,4]triazolo[4,3-a]pyridin-3-yl}piperidin-4-yl)thiophene-2-carboxamide

IUPAC name

5-chloro-N-(1-{[124]triazolo[43-a]pyridin-3-yl}piperidin-4-yl)thiophene-2-carboxamide

SMILES

O=C(c(s1)ccc1Cl)NC(CC1)CCN1c1nnc2n1cccc2

InChI

InChI=1S/C16H16ClN5OS/c17-13-5-4-12(24-13)15(23)18-11-6-9-21(10-7-11)16-20-19-14-3-1-2-8-22(14)16/h1-5,8,11H,6-7,9-10H2,(H,18,23)

InChI Key

PVQQHJJIZHVEQY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27619809

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.85

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.597

Distribution Coefficient, logD

2.597

Water Solubility, LogSw

-3.39

Polar Surface Area

49.807

Acid Dissociation Constant (pKa)

13.89

Base Dissociation Constant (pKb)

3.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.30

T404-1539 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Agro:
  • Agro
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with T404-1539 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T404-1539?
Check Price and Availability of T404-1539, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T404-1539 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T404-1539
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T404-1539
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T404-1539 available by request