T424-0241 Screening compound: 1-(1-methyl-6-oxo-1,6-dihydro-4-pyridazinyl)-N-(3-pyridylmethyl)-3-piperidinecarboxamide

T424-0241 Screening compound: 1-(1-methyl-6-oxo-1,6-dihydro-4-pyridazinyl)-N-(3-pyridylmethyl)-3-piperidinecarboxamide
T424-0241 Screening compound: 1-(1-methyl-6-oxo-1,6-dihydro-4-pyridazinyl)-N-(3-pyridylmethyl)-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T424-0241
1-(1-methyl-6-oxo-1,6-dihydro-4-pyridazinyl)-N-(3-pyridylmethyl)-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T424-0241

Molecular Formula

C17H21N5O2 (C17 H21 N5 O2)

Compound Name

1-(1-methyl-6-oxo-1,6-dihydro-4-pyridazinyl)-N-(3-pyridylmethyl)-3-piperidinecarboxamide

IUPAC name

1-(1-methyl-6-oxo-16-dihydropyridazin-4-yl)-N-[(pyridin-3-yl)methyl]piperidine-3-carboxamide

SMILES

CN1N=CC(N(CCC2)CC2C(NCc2cnccc2)=O)=CC1=O

InChI

InChI=1S/C17H21N5O2/c1-21-16(23)8-15(11-20-21)22-7-3-5-14(12-22)17(24)19-10-13-4-2-6-18-9-13/h2,4,6,8-9,11,14H,3,5,7,10,12H2,1H3,(H,19,24)/t14-/m0/s1

InChI Key

QRLREGAQGDZAAL-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27620990

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

327.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

-0.270

Distribution Coefficient, logD

-0.290

Water Solubility, LogSw

-0.77

Polar Surface Area

66.309

Acid Dissociation Constant (pKa)

13.29

Base Dissociation Constant (pKb)

6.09

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.18

T424-0241 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with T424-0241 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T424-0241?
Check Price and Availability of T424-0241, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T424-0241 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T424-0241
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T424-0241
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T424-0241 available by request