T425-0883 Screening compound: 8-[8-(4-fluorophenyl)imidazo[1,2-a]pyrazine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

T425-0883 Screening compound: 8-[8-(4-fluorophenyl)imidazo[1,2-a]pyrazine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane
T425-0883 Screening compound: 8-[8-(4-fluorophenyl)imidazo[1,2-a]pyrazine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound T425-0883
8-[8-(4-fluorophenyl)imidazo[1,2-a]pyrazine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T425-0883

Molecular Formula

C20H19FN4O3 (C20 H19 FN4 O3)

Compound Name

8-[8-(4-fluorophenyl)imidazo[1,2-a]pyrazine-2-carbonyl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-[8-(4-fluorophenyl)imidazo[12-a]pyrazine-2-carbonyl]-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c1cn(ccnc2-c(cc3)ccc3F)c2n1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C20H19FN4O3/c21-15-3-1-14(2-4-15)17-18-23-16(13-25(18)10-7-22-17)19(26)24-8-5-20(6-9-24)27-11-12-28-20/h1-4,7,10,13H,5-6,8-9,11-12H2

InChI Key

LRZDDCAJQFVLCD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29022751

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.694

Distribution Coefficient, logD

1.694

Water Solubility, LogSw

-1.68

Polar Surface Area

51.083

Acid Dissociation Constant (pKa)

27.37

Base Dissociation Constant (pKb)

2.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

T425-0883 in Drug Discovery

Included in Screening Libraries

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T425-0883 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T425-0883?
Check Price and Availability of T425-0883, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T425-0883 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T425-0883
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T425-0883
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T425-0883 available by request