T427-0888 Screening compound: N~1~-(4-{[3-(4-fluorophenyl)-4-methylpiperazino]sulfonyl}phenyl)acetamide

T427-0888 Screening compound: N~1~-(4-{[3-(4-fluorophenyl)-4-methylpiperazino]sulfonyl}phenyl)acetamide
T427-0888 Screening compound: N~1~-(4-{[3-(4-fluorophenyl)-4-methylpiperazino]sulfonyl}phenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T427-0888
N~1~-(4-{[3-(4-fluorophenyl)-4-methylpiperazino]sulfonyl}phenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T427-0888

Molecular Formula

C19H22FN3O3S (C19 H22 FN3 O3 S)

Compound Name

N~1~-(4-{[3-(4-fluorophenyl)-4-methylpiperazino]sulfonyl}phenyl)acetamide

IUPAC name

n/a

SMILES

CC(Nc(cc1)ccc1S(N1CC(c(cc2)ccc2F)N(C)CC1)(=O)=O)=O

InChI

InChI=1S/C19H22FN3O3S/c1-14(24)21-17-7-9-18(10-8-17)27(25,26)23-12-11-22(2)19(13-23)15-3-5-16(20)6-4-15/h3-10,19H,11-13H2,1-2H3,(H,21,24)/t19-/m0/s1

InChI Key

QOGZCANRRXXMEU-IBGZPJMESA-N

MDL Number (MFCD)

MFCD27621048

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.47

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.759

Distribution Coefficient, logD

1.756

Water Solubility, LogSw

-2.67

Polar Surface Area

58.260

Acid Dissociation Constant (pKa)

10.53

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.60

T427-0888 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T427-0888 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T427-0888?
Check Price and Availability of T427-0888, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T427-0888 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T427-0888
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T427-0888
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T427-0888 available by request