T473-0839 Screening compound: 1-{3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-7-yl}-4-(thiophene-2-sulfonyl)piperazine

T473-0839 Screening compound: 1-{3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-7-yl}-4-(thiophene-2-sulfonyl)piperazine
T473-0839 Screening compound: 1-{3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-7-yl}-4-(thiophene-2-sulfonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound T473-0839
1-{3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-7-yl}-4-(thiophene-2-sulfonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T473-0839

Molecular Formula

C16H18N6O2S2 (C16 H18 N6 O2 S2)

Compound Name

1-{3-cyclopropyl-[1,2,4]triazolo[4,3-b]pyridazin-7-yl}-4-(thiophene-2-sulfonyl)piperazine

IUPAC name

1-{3-cyclopropyl-[124]triazolo[43-b]pyridazin-7-yl}-4-(thiophene-2-sulfonyl)piperazine

SMILES

O=S(c1cccs1)(N(CC1)CCN1c1cc2nnc(C3CC3)n2nc1)=O

InChI

InChI=1S/C16H18N6O2S2/c23-26(24,15-2-1-9-25-15)21-7-5-20(6-8-21)13-10-14-18-19-16(12-3-4-12)22(14)17-11-13/h1-2,9-12H,3-8H2

InChI Key

NQZSBYRDTJLMQV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024274

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.503

Distribution Coefficient, logD

1.503

Water Solubility, LogSw

-2.13

Polar Surface Area

69.134

Acid Dissociation Constant (pKa)

21.57

Base Dissociation Constant (pKb)

5.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.80

T473-0839 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T473-0839 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T473-0839?
Check Price and Availability of T473-0839, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T473-0839 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T473-0839
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T473-0839
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T473-0839 available by request