T473-1498 Screening compound: 3-CYCLOPROPYL-7-{4-[(1-ETHYL-5-METHYL-1H-PYRAZOL-4-YL)METHYL]PIPERAZINO}[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE

T473-1498 Screening compound: 3-CYCLOPROPYL-7-{4-[(1-ETHYL-5-METHYL-1H-PYRAZOL-4-YL)METHYL]PIPERAZINO}[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE
T473-1498 Screening compound: 3-CYCLOPROPYL-7-{4-[(1-ETHYL-5-METHYL-1H-PYRAZOL-4-YL)METHYL]PIPERAZINO}[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound T473-1498
3-CYCLOPROPYL-7-{4-[(1-ETHYL-5-METHYL-1H-PYRAZOL-4-YL)METHYL]PIPERAZINO}[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T473-1498

Molecular Formula

C19H26N8 (C19 H26 N8)

Compound Name

3-CYCLOPROPYL-7-{4-[(1-ETHYL-5-METHYL-1H-PYRAZOL-4-YL)METHYL]PIPERAZINO}[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE

IUPAC name

n/a

SMILES

CCn1ncc(CN(CC2)CCN2c2cc3nnc(C4CC4)n3nc2)c1C

InChI

InChI=1S/C19H26N8/c1-3-26-14(2)16(11-20-26)13-24-6-8-25(9-7-24)17-10-18-22-23-19(15-4-5-15)27(18)21-12-17/h10-12,15H,3-9,13H2,1-2H3

InChI Key

XZILAPVEFYFWDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024191

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

366.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.090

Distribution Coefficient, logD

-2.787

Water Solubility, LogSw

-1.07

Polar Surface Area

54.062

Acid Dissociation Constant (pKa)

21.57

Base Dissociation Constant (pKb)

11.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.90

T473-1498 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T473-1498 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T473-1498?
Check Price and Availability of T473-1498, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T473-1498 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T473-1498
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T473-1498
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T473-1498 available by request