T475-0286 Screening compound: 2-(4-cyclohexylpiperazine-1-carbonyl)-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one

T475-0286 Screening compound: 2-(4-cyclohexylpiperazine-1-carbonyl)-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one
T475-0286 Screening compound: 2-(4-cyclohexylpiperazine-1-carbonyl)-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T475-0286
2-(4-cyclohexylpiperazine-1-carbonyl)-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T475-0286

Molecular Formula

C20H27N5O2 (C20 H27 N5 O2)

Compound Name

2-(4-cyclohexylpiperazine-1-carbonyl)-4-ethyl-3H,4H-pyrido[2,3-b]pyrazin-3-one

IUPAC name

2-(4-cyclohexylpiperazine-1-carbonyl)-4-ethyl-3H4H-pyrido[23-b]pyrazin-3-one

SMILES

CCN(c1ncccc1N=C1C(N(CC2)CCN2C2CCCCC2)=O)C1=O

InChI

InChI=1S/C20H27N5O2/c1-2-25-18-16(9-6-10-21-18)22-17(20(25)27)19(26)24-13-11-23(12-14-24)15-7-4-3-5-8-15/h6,9-10,15H,2-5,7-8,11-14H2,1H3

InChI Key

PYZLVANCDRKCJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27621433

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.709

Distribution Coefficient, logD

1.652

Water Solubility, LogSw

-1.85

Polar Surface Area

53.519

Acid Dissociation Constant (pKa)

24.77

Base Dissociation Constant (pKb)

6.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

T475-0286 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T475-0286 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T475-0286?
Check Price and Availability of T475-0286, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T475-0286 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T475-0286
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T475-0286
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T475-0286 available by request