T480-0015 Screening compound: 1-[5-METHYL-4-(PYRROLIDIN-1-YL)THIENO[3,4-D]PYRIMIDINE-2-CARBONYL]-4-(PYRIDIN-2-YL)PIPERAZINE

T480-0015 Screening compound: 1-[5-METHYL-4-(PYRROLIDIN-1-YL)THIENO[3,4-D]PYRIMIDINE-2-CARBONYL]-4-(PYRIDIN-2-YL)PIPERAZINE
T480-0015 Screening compound: 1-[5-METHYL-4-(PYRROLIDIN-1-YL)THIENO[3,4-D]PYRIMIDINE-2-CARBONYL]-4-(PYRIDIN-2-YL)PIPERAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound T480-0015
1-[5-METHYL-4-(PYRROLIDIN-1-YL)THIENO[3,4-D]PYRIMIDINE-2-CARBONYL]-4-(PYRIDIN-2-YL)PIPERAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T480-0015

Molecular Formula

C21H24N6OS (C21 H24 N6 OS)

Compound Name

1-[5-METHYL-4-(PYRROLIDIN-1-YL)THIENO[3,4-D]PYRIMIDINE-2-CARBONYL]-4-(PYRIDIN-2-YL)PIPERAZINE

IUPAC name

n/a

SMILES

Cc1c2c(N3CCCC3)nc(C(N(CC3)CCN3c3ncccc3)=O)nc2cs1

InChI

InChI=1S/C21H24N6OS/c1-15-18-16(14-29-15)23-19(24-20(18)26-8-4-5-9-26)21(28)27-12-10-25(11-13-27)17-6-2-3-7-22-17/h2-3,6-7,14H,4-5,8-13H2,1H3

InChI Key

MBACQGMINOYHMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29027509

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.901

Distribution Coefficient, logD

3.893

Water Solubility, LogSw

-4.05

Polar Surface Area

51.714

Acid Dissociation Constant (pKa)

21.17

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

T480-0015 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T480-0015 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T480-0015?
Check Price and Availability of T480-0015, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T480-0015 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T480-0015
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T480-0015
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T480-0015 available by request