T480-0224 Screening compound: [5-methyl-4-(4-methylpiperidino)thieno[3,4-d]pyrimidin-2-yl](4-methylpiperazino)methanone

T480-0224 Screening compound: [5-methyl-4-(4-methylpiperidino)thieno[3,4-d]pyrimidin-2-yl](4-methylpiperazino)methanone
T480-0224 Screening compound: [5-methyl-4-(4-methylpiperidino)thieno[3,4-d]pyrimidin-2-yl](4-methylpiperazino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound T480-0224
[5-methyl-4-(4-methylpiperidino)thieno[3,4-d]pyrimidin-2-yl](4-methylpiperazino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T480-0224

Molecular Formula

C19H27N5OS (C19 H27 N5 OS)

Compound Name

[5-methyl-4-(4-methylpiperidino)thieno[3,4-d]pyrimidin-2-yl](4-methylpiperazino)methanone

IUPAC name

1-methyl-4-[5-methyl-4-(4-methylpiperidin-1-yl)thieno[34-d]pyrimidine-2-carbonyl]piperazine

SMILES

CC(CC1)CCN1c1nc(C(N2CCN(C)CC2)=O)nc2csc(C)c12

InChI

InChI=1S/C19H27N5OS/c1-13-4-6-23(7-5-13)18-16-14(2)26-12-15(16)20-17(21-18)19(25)24-10-8-22(3)9-11-24/h12-13H,4-11H2,1-3H3

InChI Key

CGMJSUDGFNZFGH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024389

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.164

Distribution Coefficient, logD

3.030

Water Solubility, LogSw

-3.38

Polar Surface Area

43.053

Acid Dissociation Constant (pKa)

21.66

Base Dissociation Constant (pKb)

6.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

63.16

T480-0224 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T480-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T480-0224?
Check Price and Availability of T480-0224, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T480-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T480-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T480-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T480-0224 available by request