T480-0727 Screening compound: 4-{5-methyl-2-[4-(propan-2-yl)piperazine-1-carbonyl]thieno[3,4-d]pyrimidin-4-yl}thiomorpholine

T480-0727 Screening compound: 4-{5-methyl-2-[4-(propan-2-yl)piperazine-1-carbonyl]thieno[3,4-d]pyrimidin-4-yl}thiomorpholine
T480-0727 Screening compound: 4-{5-methyl-2-[4-(propan-2-yl)piperazine-1-carbonyl]thieno[3,4-d]pyrimidin-4-yl}thiomorpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound T480-0727
4-{5-methyl-2-[4-(propan-2-yl)piperazine-1-carbonyl]thieno[3,4-d]pyrimidin-4-yl}thiomorpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T480-0727

Molecular Formula

C19H27N5OS2 (C19 H27 N5 OS2)

Compound Name

4-{5-methyl-2-[4-(propan-2-yl)piperazine-1-carbonyl]thieno[3,4-d]pyrimidin-4-yl}thiomorpholine

IUPAC name

4-{5-methyl-2-[4-(propan-2-yl)piperazine-1-carbonyl]thieno[34-d]pyrimidin-4-yl}thiomorpholine

SMILES

CC(C)N(CC1)CCN1C(c1nc2csc(C)c2c(N2CCSCC2)n1)=O

InChI

InChI=1S/C19H27N5OS2/c1-13(2)22-4-6-24(7-5-22)19(25)17-20-15-12-27-14(3)16(15)18(21-17)23-8-10-26-11-9-23/h12-13H,4-11H2,1-3H3

InChI Key

UQVPNQBPIRWYOV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29026148

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.094

Distribution Coefficient, logD

2.756

Water Solubility, LogSw

-3.19

Polar Surface Area

43.441

Acid Dissociation Constant (pKa)

22.34

Base Dissociation Constant (pKb)

7.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

63.20

T480-0727 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with T480-0727 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T480-0727?
Check Price and Availability of T480-0727, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T480-0727 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T480-0727
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T480-0727
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T480-0727 available by request