T482-0419 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2-(3-methoxyphenyl)acetamide

T482-0419 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2-(3-methoxyphenyl)acetamide
T482-0419 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2-(3-methoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-0419
N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2-(3-methoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-0419

Molecular Formula

C18H18N4O2 (C18 H18 N4 O2)

Compound Name

N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2-(3-methoxyphenyl)acetamide

IUPAC name

N-{2-cyclopropyl-[124]triazolo[15-a]pyridin-8-yl}-2-(3-methoxyphenyl)acetamide

SMILES

COc1cccc(CC(Nc2cccn3nc(C4CC4)nc23)=O)c1

InChI

InChI=1S/C18H18N4O2/c1-24-14-5-2-4-12(10-14)11-16(23)19-15-6-3-9-22-18(15)20-17(21-22)13-7-8-13/h2-6,9-10,13H,7-8,11H2,1H3,(H,19,23)

InChI Key

ZIGKKODMVPSMON-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024357

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.260

Distribution Coefficient, logD

2.257

Water Solubility, LogSw

-2.88

Polar Surface Area

51.902

Acid Dissociation Constant (pKa)

9.78

Base Dissociation Constant (pKb)

4.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

T482-0419 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Agro:
  • Agro
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T482-0419 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-0419?
Check Price and Availability of T482-0419, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-0419 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-0419
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-0419
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-0419 available by request