T482-0628 Screening compound: N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(2-methoxyphenyl)propanamide

T482-0628 Screening compound: N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(2-methoxyphenyl)propanamide
T482-0628 Screening compound: N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(2-methoxyphenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-0628
N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(2-methoxyphenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-0628

Molecular Formula

C20H22N4O2 (C20 H22 N4 O2)

Compound Name

N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(2-methoxyphenyl)propanamide

IUPAC name

N-{2-cyclobutyl-[124]triazolo[15-a]pyridin-8-yl}-3-(2-methoxyphenyl)propanamide

SMILES

COc1c(CCC(Nc2cccn3nc(C4CCC4)nc23)=O)cccc1

InChI

InChI=1S/C20H22N4O2/c1-26-17-10-3-2-6-14(17)11-12-18(25)21-16-9-5-13-24-20(16)22-19(23-24)15-7-4-8-15/h2-3,5-6,9-10,13,15H,4,7-8,11-12H2,1H3,(H,21,25)

InChI Key

QWJSJILHXYDERI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29028296

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.528

Distribution Coefficient, logD

2.526

Water Solubility, LogSw

-2.76

Polar Surface Area

51.989

Acid Dissociation Constant (pKa)

9.80

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

T482-0628 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T482-0628 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-0628?
Check Price and Availability of T482-0628, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-0628 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-0628
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-0628
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-0628 available by request