T482-1357 Screening compound: 3-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[(3-methoxyphenyl)methyl]urea

T482-1357 Screening compound: 3-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[(3-methoxyphenyl)methyl]urea
T482-1357 Screening compound: 3-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[(3-methoxyphenyl)methyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-1357
3-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[(3-methoxyphenyl)methyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-1357

Molecular Formula

C19H21N5O2 (C19 H21 N5 O2)

Compound Name

3-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[(3-methoxyphenyl)methyl]urea

IUPAC name

3-{2-cyclobutyl-[124]triazolo[15-a]pyridin-8-yl}-1-[(3-methoxyphenyl)methyl]urea

SMILES

COc1cccc(CNC(Nc2cccn3nc(C4CCC4)nc23)=O)c1

InChI

InChI=1S/C19H21N5O2/c1-26-15-8-2-5-13(11-15)12-20-19(25)21-16-9-4-10-24-18(16)22-17(23-24)14-6-3-7-14/h2,4-5,8-11,14H,3,6-7,12H2,1H3,(H2,20,21,25)

InChI Key

JBEVCHJANAGRFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024583

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.129

Distribution Coefficient, logD

2.129

Water Solubility, LogSw

-2.78

Polar Surface Area

62.650

Acid Dissociation Constant (pKa)

11.74

Base Dissociation Constant (pKb)

4.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

T482-1357 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with T482-1357 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-1357?
Check Price and Availability of T482-1357, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-1357 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-1357
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-1357
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-1357 available by request