T482-1629 Screening compound: 3-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[3-(trifluoromethyl)phenyl]urea

T482-1629 Screening compound: 3-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[3-(trifluoromethyl)phenyl]urea
T482-1629 Screening compound: 3-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[3-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-1629
3-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[3-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-1629

Molecular Formula

C14H10F3N5O (C14 H10 F3 N5 O)

Compound Name

3-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-[3-(trifluoromethyl)phenyl]urea

IUPAC name

3-{[124]triazolo[15-a]pyridin-8-yl}-1-[3-(trifluoromethyl)phenyl]urea

SMILES

O=C(Nc1cccc(C(F)(F)F)c1)Nc1cccn2ncnc12

InChI

InChI=1S/C14H10F3N5O/c15-14(16,17)9-3-1-4-10(7-9)20-13(23)21-11-5-2-6-22-12(11)18-8-19-22/h1-8H,(H2,20,21,23)

InChI Key

NZZVFLMFPKHERG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024595

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

321.26

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.858

Distribution Coefficient, logD

2.858

Water Solubility, LogSw

-3.36

Polar Surface Area

54.473

Acid Dissociation Constant (pKa)

11.22

Base Dissociation Constant (pKb)

2.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

T482-1629 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T482-1629 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-1629?
Check Price and Availability of T482-1629, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-1629 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-1629
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-1629
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-1629 available by request