T482-1879 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2,1,3-benzothiadiazole-4-sulfonamide

T482-1879 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2,1,3-benzothiadiazole-4-sulfonamide
T482-1879 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2,1,3-benzothiadiazole-4-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-1879
N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2,1,3-benzothiadiazole-4-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-1879

Molecular Formula

C15H12N6O2S2 (C15 H12 N6 O2 S2)

Compound Name

N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-2,1,3-benzothiadiazole-4-sulfonamide

IUPAC name

N-{2-cyclopropyl-[124]triazolo[15-a]pyridin-8-yl}-213-benzothiadiazole-4-sulfonamide

SMILES

O=S(c1cccc2nsnc12)(Nc1cccn2nc(C3CC3)nc12)=O

InChI

InChI=1S/C15H12N6O2S2/c22-25(23,12-5-1-3-10-13(12)19-24-18-10)20-11-4-2-8-21-15(11)16-14(17-21)9-6-7-9/h1-5,8-9,20H,6-7H2

InChI Key

GFCMQBJICRCDLO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024627

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.172

Distribution Coefficient, logD

1.251

Water Solubility, LogSw

-2.59

Polar Surface Area

83.083

Acid Dissociation Constant (pKa)

7.23

Base Dissociation Constant (pKb)

6.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

T482-1879 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T482-1879 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-1879?
Check Price and Availability of T482-1879, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-1879 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-1879
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-1879
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-1879 available by request