T482-1916 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

T482-1916 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide
T482-1916 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-1916
N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-1916

Molecular Formula

C18H17N5O3S (C18 H17 N5 O3 S)

Compound Name

N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-1-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

IUPAC name

N-{2-cyclopropyl-[124]triazolo[15-a]pyridin-8-yl}-1-methyl-2-oxo-23-dihydro-1H-indole-5-sulfonamide

SMILES

CN(C(C1)=O)c(cc2)c1cc2S(Nc1cccn2nc(C3CC3)nc12)(=O)=O

InChI

InChI=1S/C18H17N5O3S/c1-22-15-7-6-13(9-12(15)10-16(22)24)27(25,26)21-14-3-2-8-23-18(14)19-17(20-23)11-4-5-11/h2-3,6-9,11,21H,4-5,10H2,1H3

InChI Key

GAXWABSQICTYTR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024636

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.451

Distribution Coefficient, logD

1.131

Water Solubility, LogSw

-2.54

Polar Surface Area

77.914

Acid Dissociation Constant (pKa)

7.36

Base Dissociation Constant (pKb)

6.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

T482-1916 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PI3K-Targeted Library (17255 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
  • GPCR
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T482-1916 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-1916?
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What is the minimum amount of T482-1916 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-1916
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-1916
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-1916 available by request