T482-1918 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(trifluoromethyl)benzene-1-sulfonamide

T482-1918 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(trifluoromethyl)benzene-1-sulfonamide
T482-1918 Screening compound: N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(trifluoromethyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-1918
N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(trifluoromethyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-1918

Molecular Formula

C16H13F3N4O2S (C16 H13 F3 N4 O2 S)

Compound Name

N-{2-cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}-3-(trifluoromethyl)benzene-1-sulfonamide

IUPAC name

N-{2-cyclopropyl-[124]triazolo[15-a]pyridin-8-yl}-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES

O=S(c1cc(C(F)(F)F)ccc1)(Nc1cccn2nc(C3CC3)nc12)=O

InChI

InChI=1S/C16H13F3N4O2S/c17-16(18,19)11-3-1-4-12(9-11)26(24,25)22-13-5-2-8-23-15(13)20-14(21-23)10-6-7-10/h1-5,8-10,22H,6-7H2

InChI Key

FVWCBGGFABLGKE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024637

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.37

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.058

Distribution Coefficient, logD

2.100

Water Solubility, LogSw

-3.51

Polar Surface Area

62.130

Acid Dissociation Constant (pKa)

6.49

Base Dissociation Constant (pKb)

6.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

T482-1918 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-infective Library (19449 compounds)

PI3K-Targeted Library (17255 compounds)

RNA-Protein Interaction Inhibitors Library (1986 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with T482-1918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-1918?
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What is the minimum amount of T482-1918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-1918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-1918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-1918 available by request