T482-1948 Screening compound: 1-(4-chlorophenyl)-N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanesulfonamide

T482-1948 Screening compound: 1-(4-chlorophenyl)-N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanesulfonamide
T482-1948 Screening compound: 1-(4-chlorophenyl)-N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-1948
1-(4-chlorophenyl)-N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-1948

Molecular Formula

C17H17ClN4O2S (C17 H17 ClN4 O2 S)

Compound Name

1-(4-chlorophenyl)-N-{2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-yl}methanesulfonamide

IUPAC name

1-(4-chlorophenyl)-N-{2-cyclobutyl-[124]triazolo[15-a]pyridin-8-yl}methanesulfonamide

SMILES

O=S(Cc(cc1)ccc1Cl)(Nc1cccn2nc(C3CCC3)nc12)=O

InChI

InChI=1S/C17H17ClN4O2S/c18-14-8-6-12(7-9-14)11-25(23,24)21-15-5-2-10-22-17(15)19-16(20-22)13-3-1-4-13/h2,5-10,13,21H,1,3-4,11H2

InChI Key

NEKLHUQUFRCFND-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29024639

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.87

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.751

Distribution Coefficient, logD

1.698

Water Solubility, LogSw

-3.54

Polar Surface Area

63.757

Acid Dissociation Constant (pKa)

6.39

Base Dissociation Constant (pKb)

5.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

T482-1948 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with T482-1948 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-1948?
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What is the minimum amount of T482-1948 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-1948
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-1948
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-1948 available by request