T482-2539 Screening compound: 2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-amine

T482-2539 Screening compound: 2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-amine
T482-2539 Screening compound: 2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-2539
2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-2539

Molecular Formula

C10H12N4 (C10 H12 N4)

Compound Name

2-cyclobutyl-[1,2,4]triazolo[1,5-a]pyridin-8-amine

IUPAC name

2-cyclobutyl-[124]triazolo[15-a]pyridin-8-amine

SMILES

Nc1cccn2nc(C3CCC3)nc12

InChI

InChI=1S/C10H12N4/c11-8-5-2-6-14-10(8)12-9(13-14)7-3-1-4-7/h2,5-7H,1,3-4,11H2

InChI Key

MGDWOEJECQTOTN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD26621434

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

188.23

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

0.814

Distribution Coefficient, logD

0.813

Water Solubility, LogSw

-0.68

Polar Surface Area

42.275

Acid Dissociation Constant (pKa)

20.09

Base Dissociation Constant (pKb)

4.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

T482-2539 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T482-2539 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-2539?
Check Price and Availability of T482-2539, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-2539 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-2539
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-2539
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-2539 available by request