T482-3749 Screening compound: 1-(1-ethyl-1H-pyrazole-3-carbonyl)-N-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}piperidin-4-amine

T482-3749 Screening compound: 1-(1-ethyl-1H-pyrazole-3-carbonyl)-N-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}piperidin-4-amine
T482-3749 Screening compound: 1-(1-ethyl-1H-pyrazole-3-carbonyl)-N-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}piperidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound T482-3749
1-(1-ethyl-1H-pyrazole-3-carbonyl)-N-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}piperidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T482-3749

Molecular Formula

C17H21N7O (C17 H21 N7 O)

Compound Name

1-(1-ethyl-1H-pyrazole-3-carbonyl)-N-{[1,2,4]triazolo[1,5-a]pyridin-8-yl}piperidin-4-amine

IUPAC name

1-(1-ethyl-1H-pyrazole-3-carbonyl)-N-{[124]triazolo[15-a]pyridin-8-yl}piperidin-4-amine

SMILES

CCn(cc1)nc1C(N(CC1)CCC1Nc1cccn2ncnc12)=O

InChI

InChI=1S/C17H21N7O/c1-2-23-11-7-15(21-23)17(25)22-9-5-13(6-10-22)20-14-4-3-8-24-16(14)18-12-19-24/h3-4,7-8,11-13,20H,2,5-6,9-10H2,1H3

InChI Key

NDODHVAQIBWWIY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29030345

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

339.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.455

Distribution Coefficient, logD

0.455

Water Solubility, LogSw

-1.74

Polar Surface Area

62.971

Acid Dissociation Constant (pKa)

21.15

Base Dissociation Constant (pKb)

3.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

T482-3749 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with T482-3749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T482-3749?
Check Price and Availability of T482-3749, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T482-3749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T482-3749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T482-3749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T482-3749 available by request