T499-0357 Screening compound: 2-cyclopentyl-1-(3-{3-propyl-3H-imidazo[4,5-b]pyridin-2-yl}pyrrolidin-1-yl)ethan-1-one

T499-0357 Screening compound: 2-cyclopentyl-1-(3-{3-propyl-3H-imidazo[4,5-b]pyridin-2-yl}pyrrolidin-1-yl)ethan-1-one
T499-0357 Screening compound: 2-cyclopentyl-1-(3-{3-propyl-3H-imidazo[4,5-b]pyridin-2-yl}pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T499-0357
2-cyclopentyl-1-(3-{3-propyl-3H-imidazo[4,5-b]pyridin-2-yl}pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T499-0357

Molecular Formula

C20H28N4O (C20 H28 N4 O)

Compound Name

2-cyclopentyl-1-(3-{3-propyl-3H-imidazo[4,5-b]pyridin-2-yl}pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-cyclopentyl-1-(3-{3-propyl-3H-imidazo[45-b]pyridin-2-yl}pyrrolidin-1-yl)ethan-1-one

SMILES

CCCn1c(nccc2)c2nc1C(CC1)CN1C(CC1CCCC1)=O

InChI

InChI=1S/C20H28N4O/c1-2-11-24-19(22-17-8-5-10-21-20(17)24)16-9-12-23(14-16)18(25)13-15-6-3-4-7-15/h5,8,10,15-16H,2-4,6-7,9,11-14H2,1H3/t16-/m1/s1

InChI Key

WMJNKLJKPFAUGQ-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD29025951

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.466

Distribution Coefficient, logD

3.466

Water Solubility, LogSw

-3.54

Polar Surface Area

37.031

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

3.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

65.00

T499-0357 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with T499-0357 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T499-0357?
Check Price and Availability of T499-0357, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T499-0357 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T499-0357
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T499-0357
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T499-0357 available by request