T500-1309 Screening compound: N~9~-(2-fluorophenyl)-4-(4-methoxybenzyl)-1-oxa-9-azaspiro[5.5]undecane-9-carboxamide

T500-1309 Screening compound: N~9~-(2-fluorophenyl)-4-(4-methoxybenzyl)-1-oxa-9-azaspiro[5.5]undecane-9-carboxamide
T500-1309 Screening compound: N~9~-(2-fluorophenyl)-4-(4-methoxybenzyl)-1-oxa-9-azaspiro[5.5]undecane-9-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T500-1309
N~9~-(2-fluorophenyl)-4-(4-methoxybenzyl)-1-oxa-9-azaspiro[5.5]undecane-9-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T500-1309

Molecular Formula

C24H29FN2O3 (C24 H29 FN2 O3)

Compound Name

N~9~-(2-fluorophenyl)-4-(4-methoxybenzyl)-1-oxa-9-azaspiro[5.5]undecane-9-carboxamide

IUPAC name

n/a

SMILES

COc1ccc(CC2CC(CC3)(CCN3C(Nc(cccc3)c3F)=O)OCC2)cc1

InChI

InChI=1S/C24H29FN2O3/c1-29-20-8-6-18(7-9-20)16-19-10-15-30-24(17-19)11-13-27(14-12-24)23(28)26-22-5-3-2-4-21(22)25/h2-9,19H,10-17H2,1H3,(H,26,28)/t19-/m0/s1

InChI Key

CGJXZRMGTKDLLF-IBGZPJMESA-N

MDL Number (MFCD)

MFCD29015689

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.747

Distribution Coefficient, logD

4.747

Water Solubility, LogSw

-4.36

Polar Surface Area

38.884

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

-1.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.80

T500-1309 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Spiro Library (21655 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T500-1309 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T500-1309?
Check Price and Availability of T500-1309, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T500-1309 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T500-1309
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T500-1309
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T500-1309 available by request