T501-1259 Screening compound: 9-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidine-1-carbonyl)-1,2,3,4-tetrahydroacridine

T501-1259 Screening compound: 9-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidine-1-carbonyl)-1,2,3,4-tetrahydroacridine
T501-1259 Screening compound: 9-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidine-1-carbonyl)-1,2,3,4-tetrahydroacridine alternative view

Chemical Structure Depiction of ChemDiv screening compound T501-1259
9-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidine-1-carbonyl)-1,2,3,4-tetrahydroacridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T501-1259

Molecular Formula

C26H31N5O (C26 H31 N5 O)

Compound Name

9-(3-{[4-(cyclopropylmethyl)-4H-1,2,4-triazol-3-yl]methyl}piperidine-1-carbonyl)-1,2,3,4-tetrahydroacridine

IUPAC name

9-(3-{[4-(cyclopropylmethyl)-4H-124-triazol-3-yl]methyl}piperidine-1-carbonyl)-1234-tetrahydroacridine

SMILES

O=C(c1c(CCCC2)c2nc2ccccc12)N1CC(Cc2nncn2CC2CC2)CCC1

InChI

InChI=1S/C26H31N5O/c32-26(25-20-7-1-3-9-22(20)28-23-10-4-2-8-21(23)25)30-13-5-6-19(16-30)14-24-29-27-17-31(24)15-18-11-12-18/h1,3,7,9,17-19H,2,4-6,8,10-16H2/t19-/m1/s1

InChI Key

LRSVVIISBRVZCS-LJQANCHMSA-N

MDL Number (MFCD)

MFCD31983414

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.049

Distribution Coefficient, logD

4.043

Water Solubility, LogSw

-4.48

Polar Surface Area

52.156

Acid Dissociation Constant (pKa)

20.19

Base Dissociation Constant (pKb)

5.56

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

53.85

T501-1259 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T501-1259 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T501-1259?
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What is the minimum amount of T501-1259 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T501-1259
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T501-1259
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T501-1259 available by request