T503-0387 Screening compound: 2-(4-{5-cyclopropyl-5H-thieno[2,3-c]pyrrole-2-carbonyl}piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

T503-0387 Screening compound: 2-(4-{5-cyclopropyl-5H-thieno[2,3-c]pyrrole-2-carbonyl}piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one
T503-0387 Screening compound: 2-(4-{5-cyclopropyl-5H-thieno[2,3-c]pyrrole-2-carbonyl}piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound T503-0387
2-(4-{5-cyclopropyl-5H-thieno[2,3-c]pyrrole-2-carbonyl}piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T503-0387

Molecular Formula

C20H26N4O2S (C20 H26 N4 O2 S)

Compound Name

2-(4-{5-cyclopropyl-5H-thieno[2,3-c]pyrrole-2-carbonyl}piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

IUPAC name

2-(4-{5-cyclopropyl-5H-thieno[23-c]pyrrole-2-carbonyl}piperazin-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one

SMILES

O=C(CN(CC1)CCN1C(c1cc2cn(C3CC3)cc2s1)=O)N1CCCC1

InChI

InChI=1S/C20H26N4O2S/c25-19(22-5-1-2-6-22)14-21-7-9-23(10-8-21)20(26)17-11-15-12-24(16-3-4-16)13-18(15)27-17/h11-13,16H,1-10,14H2

InChI Key

VRYKEWCMLBVAQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29026087

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.800

Distribution Coefficient, logD

1.795

Water Solubility, LogSw

-2.35

Polar Surface Area

41.869

Acid Dissociation Constant (pKa)

24.76

Base Dissociation Constant (pKb)

5.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

T503-0387 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Soluble Diversity Library (15920 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with T503-0387 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T503-0387?
Check Price and Availability of T503-0387, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T503-0387 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T503-0387
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T503-0387
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T503-0387 available by request