T508-0028 Screening compound: N-(cyclopropylmethyl)-5-oxo-7-phenyl-N-propyl-1,2,3,5-tetrahydroindolizine-8-carboxamide

T508-0028 Screening compound: N-(cyclopropylmethyl)-5-oxo-7-phenyl-N-propyl-1,2,3,5-tetrahydroindolizine-8-carboxamide
T508-0028 Screening compound: N-(cyclopropylmethyl)-5-oxo-7-phenyl-N-propyl-1,2,3,5-tetrahydroindolizine-8-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound T508-0028
N-(cyclopropylmethyl)-5-oxo-7-phenyl-N-propyl-1,2,3,5-tetrahydroindolizine-8-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

T508-0028

Molecular Formula

C22H26N2O2 (C22 H26 N2 O2)

Compound Name

N-(cyclopropylmethyl)-5-oxo-7-phenyl-N-propyl-1,2,3,5-tetrahydroindolizine-8-carboxamide

IUPAC name

N-(cyclopropylmethyl)-5-oxo-7-phenyl-N-propyl-1235-tetrahydroindolizine-8-carboxamide

SMILES

CCCN(CC1CC1)C(C(C(c1ccccc1)=C1)=C(CCC2)N2C1=O)=O

InChI

InChI=1S/C22H26N2O2/c1-2-12-23(15-16-10-11-16)22(26)21-18(17-7-4-3-5-8-17)14-20(25)24-13-6-9-19(21)24/h3-5,7-8,14,16H,2,6,9-13,15H2,1H3

InChI Key

QGUDNIRYIBAJIK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31983707

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.359

Distribution Coefficient, logD

3.359

Water Solubility, LogSw

-3.55

Polar Surface Area

33.807

Acid Dissociation Constant (pKa)

23.13

Base Dissociation Constant (pKb)

3.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.46

T508-0028 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with T508-0028 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound T508-0028?
Check Price and Availability of T508-0028, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of T508-0028 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for T508-0028
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for T508-0028
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of T508-0028 available by request